Allergic Rhinitis
Hay fever, or allergy to pollen, mold, dander, or dust, can have you running for the tissues.
With allergic rhinitis, cells in your nasal mucous membranes release histamine. This chemical acts on various nerves within the nasal mucous membranes, which causes you to sneeze. It also causes other typical allergy-related problems, like a runny nose.
Antihistamines, in both oral and nasal forms, are often good treatment choices for sneezing caused by allergic rhinitis. They work against the histamine that is producing the sneezing and runny nose.
You should also take physical measures to reduce the allergens that are producing the reaction. These can include ensuring your furnace filters are clean, using air filters to reduce the amount of pollen in indoor air, and washing your linens in hot water to kill dust mites.
Infections
Respiratory tract infections, such as the common cold, can also cause sneezing. Colds cause mucus production, which in turn stimulates various nerves within the nasal mucous membranes.
This is one of the reasons it can sometimes be hard to distinguish a cold from allergies.
In the case of a cold, histamine is not causing the sneezing, so most antihistamines won’t help. However, those that can dry nasal secretions (like Benadryl) might. Anticholinergic nasal sprays, such as Nasal Atrovent, can also help ease sneezing.
Irritants and Other Sneezing Triggers
Remember those old cartoons when black pepper was used to launch a character into a sneezing attack? Black pepper acts as a chemical irritant on the nerves in the nasal mucosa, which causes sneezing.
Other chemical irritants that cause sneezing include strong odors, perfumes, foods, and tobacco smoke. These triggers cause non-allergic rhinitis, as there are no allergic antibodies behind the symptoms.
Physical irritants such as bright sunlight can also cause sneezing. The nasoocular reflex involves a connection between the eyes and nose, which causes stimulation of nerves within the nasal mucous membranes. Sneezing is the end result.
Sneezing from chemical and physical irritants is not due to the release of histamine, so most antihistamines would not be expected to help in these cases either.
Instead, various nasal sprays, including nasal steroids, some nasal antihistamines, and anticholinergic nasal sprays may be helpful for treating sneezing caused by chemical and physical irritants.