Should the top four teams win out — Alabama, Clemson, Miami, Oklahoma — their spots will likely be secured in the CFP.
Tons of teams are on upset alert this Saturday, with only one top 25 matchup taking place — No. 25 Michigan vs. No. 5 Wisconsin.
MORE: What to know about Week 12 in college football
Follow along below with all of the top highlight reel plays from, what should be, a fun college football Saturday.
(All times Eastern.)
College football scores, highlights
11:55 p.m.: Great throw from Josh Rosen, but in the end it wasn’t enough in a 28-23 loss to USC.
11:17 p.m.: Just like they drew it up, no doubt.
10:42 p.m.: Give the kicker some love!
10:26 p.m.: Bryce Love is a walking touchdown — this one comes from 57 yards out.
9:18 p.m.: If UConn thought it was still in this game … well, it’s not anymore.
8:32 p.m.: Michael Pittman scores one of the coolest punt return touchdowns we’ve ever seen. USC up 7-0:
8:23 p.m.: This field goal wasn’t anywhere close.
8:15 p.m.: Pittsburgh pulled off this trick play during its loss to Virginia Tech.
7:48 p.m.: Louisville quarterback Lamar Jackson had this impressive run in the second quarter of the Cardinals 56-10 victory over Syracuse.
7:36 p.m.: Oregon quarterback Justin Herbert shows off the wheels.
7:33 p.m.: Stanley Morgan Jr. hauls in a pass one-handed and keeps his feet in-bounds.
7:23 p.m.: Boston College is currently playing UConn at Fenway Park.
7:11 p.m.: Kansas State upsets No. 13 Oklahoma State 45-40 on the road.
7:03 p.m.: Penn State wide receiver Juwan Johnson makes a nice one-handed catch.
6:51 p.m.: Louisville running back Malik Williams has 180 yards on just nine carries so far. Louisville leads Syracuse 49-3 with 4:43 left in the third quarter.
6:45 p.m.: Oklahoma is currently leading Kansas 38-3. Kansas fans are not happy.
6:35 p.m.: Navy almost pulls off the running back pass on fourth down but the throw falls incomplete.
6:23 p.m.: Nick Chubb with another long run for Georgia. He now has 151 yards and two touchdowns.
6:10 p.m.: J.T. Barrett with another touchdown for Ohio State.
6:01 p.m.: Georgia again scores on the ground as Sony Michel runs it in.
5:57 p.m.: Penn State adds another score against Nebraska.
5:41 p.m.: Saquon Barkley sets the Penn State program record for career rushing touchdowns on this score.
5:39 p.m.: Navy takes a 17-10 lead over No. 8 Notre Dame.
5:28 p.m.: David Montgomery breaks multiple tackles on this long run for Iowa State.
5:13 p.m.: Sony Michel breaks off another big touchdown run for Georgia.
5:04 p.m.: Brian Lewerke runs it in for Michigan State.
5:01 p.m.: Jake Fromm gives Georgia a 14-6 lead over Kentucky.
4:54 p.m.: I’m sorry, what?
4:31 p.m.: J.T. Barrett with a career milestone today.
4:24 p.m.: That’s No. 40 for Nick Chubb.
4:17 p.m.: Mike Weber’s got wheels.
4:12 p.m.: Saquon Barkley with a long touchdown run to give Penn State an early lead over Nebraska.
4:05 p.m.: How did he not go down?
3:53 p.m.: Georgia quarterback Jake Fromm throws an early pick against Kentucky.
3:45 p.m.: Virginia Tech seals a win over Pittsburgh with a goal-line stand as time expires.
3:29 p.m.: The clinching score for Miami.
3:27 p.m.: Someone’s excited for Thanksgiving dinner.
3:17 p.m.: After a valiant effort by the Cavaliers, it looks like Miami has it all locked up.
3:15 p.m.: —eyes emoji—
3:13 p.m.: Here’s a crazy scene from the Wisconsin press box.
3:03 p.m.: The Bulldogs came back to tie it in the fourth.
2:54 p.m.: Baylor gets on the board with a good play fake.
2:48 p.m.: Holy smokes.
2:46 p.m.: This is exactly how one draws it up.
2:41 p.m.: Well, this is not what you want if you’re Texas Tech.
2:34 p.m.: Ow.
2:31 p.m.: That’s a touchdown through a tight window for Wisconsin.
2:23 p.m.: We are tied in Miami following a pick six.
2:19 p.m.: Does Michigan have a turnover chain, or…
2:18 p.m.: Here comes Miami (again).
2:16 p.m.: Yep. Just like Arkansas drew it up.
2:13 p.m.: Malik Rosier has no interest in losing to the Hoos.
2:06 p.m.: After a big stop and a blocked punt, Virginia goes back up by two scores.
2:04 p.m.: ECU is bringing it to the Bearcats!
1:42 p.m.: Mercer for the upset over Alaba—
Oh wait.
1:36 p.m.: Originally called an incomplete pass, Virginia regains the lead with 30 seconds until halftime. 21-14 Cavaliers. Whoa.
1:30 p.m.: Ouch.
1:25 p.m.: Mississippi State comes back from down two scores to tie it up.
1:17 p.m.: Brandon Peters should visit a doctor with the way he coughed up this football.
After Donovan Peoples-Jones’ non-TD catch ruling was upheld, Michigan QB Brandon Peters fumbled right into the hands of @BadgerFootball: pic.twitter.com/H8TUaatvZj
1:14 p.m.: Somebody get that man an oxygen tank.
1:13 p.m.: Miami definitely doesn’t want to be upset.
1:08 p.m.: Gulp Well, then, Virginia…
1:05 p.m.: Florida State is rolling with this big-time field goal block return for the TD.
12:57 p.m.: Arkansas and Bert Bielema putting Mississippi State on upset watch.
12:55 p.m.: Calvin Ridley does it all.
12:50 p.m.: Miami doesn’t want to be upset today, as they answer with a score. 14-7 Virginia in the first.
12:46 p.m.: Wisconsin brings it back for a 50-yard punt return.
12:42 p.m.: Virginia goes up by two scores on Miami, and Kurt Benkert has a message for Hurricane fans.
12:32 p.m: Someone keep an eye — all eyes — on Garret Dooley.
12:25 p.m.: Northwestern running back Justin Jackson making it a record-breaking Saturday.
12:24 p.m.: Florida State jumps out to an early lead.
12:12 p.m.: And we have our first nice toss and catch of the day, courtesy of East Carolina.
12:10 p.m.: I believe this is an example of “smash-mouth football.”